Eyebrow Hair Restoration

Adipose Derived Stem Cells for Hair Loss Restoration

Most Frequent Questions:

  • What is the “Stem Cells Therapy” for hair loss?

Stem cells have been studied for their therapeutic potential in many medical fields, and in hair loss treatment. Stem cells applications increased rapidly during the last years, especially after discovering the adipose-derived stem cells (as SVF and Cultured ADSCs).

The Adipose(Fat)-Derived Stem Cell Therapy is an innovative treatment recommended for a wide variety of conditions from physical injuries to hair loss and even Diabetes. Yet, many people are just learning about it now for the first time. These are not embryonic stem cells or cells from foetuses, but these regenerative cells come straight from your own body, from fatty tissue that you are already wanting to get rid from it. Separation of these active cells and re-inject it back into your body and put to work to heal disease or dysfunction that affect the body area and in this case is your scalp, beard, moustache or eyebrow.

  • Why the stem cells from fatty tissue and not bone marrow?

Many studies have found that adipose-derived stem cells ADSCs have surface markers and gen profiling similar to bone marrow-derived stem cells BmSCs (the most effective mesenchymal stem cells). ADSCs have their own capacities of multidirectional differentiation, week immunogenicity, lack of morbidity at the donor site, contrary to BmSCs. Adipose tissue is rich source of stem cells and higher than bone marrow, besides, its abundance and its easy sampling, performing a small liposuction from the lower abdomen, love handle or thighs, for that, represents a significant alternative to bone marrow mesenchymal stem cells.

  • What is the advantage of stem cells therapy over the hair transplant surgery?

With stem cell therapy, we are trying to treat the bald area and help to recover the stem cells that naturally embedded in your scalp to covert to hair follicle and start near normal hair growth cycle, we are actually trying to increase the number of the hair follicles that you have in your scalp while with surgery which supposed to be the last option of treatment modality, we are not treating the baldness problem but, mostly camouflage it by redistribute the amount of hair follicles that you have by removing it from donor area which the back of your scalp and transplant it to where is the baldness patch on the scalp, beard, moustache or eyebrow. So, numbers of hair is same or even less due to fact that in hair transplant not all transplanted hair follicles are going to survive but percentage of it will be lost. 

  • Who is the good candidate for this treatment?

Any man or women suffering from hair loss, thinning of hair, wiry hair of eyebrow. from mild to severe case. Typically used for those patients who are not surgical candidates because they are too young or are in the early phase of hair loss. In severe cases who do need hair transplant, preparation the recipient bed for transplanted hair follicles to increase percentage of survival follicular grafts area by increase its blood supply and stimulate the original stem cells in the bed. At the same time strengthen the hairs in the donor area and help the donor area to heal faster.

  • What result to expect from this treatment?

ADSCs is the most advanced and promising treatment for hair restoration. Effective and safe method based on your own healing power of your own stem cells. It is a biological product and the results vary from patient to patient according to biological age of the patient.

  • What types of hair loss that best respond to this therapy?

It has effectively grown hair in the following patients group:

  • Male and female pattern hair loss
  • Alopecia areata
  • Eyebrow or beard hypotrichosis
  • Metabolic causes of hair loss, such as medication induced or iron deficiency.
  • What will happen if I have done the stem cells therapy and after it still want to do hair transplant. Is that possible?

Yes of course but, you are going to get much better result if hair transplant done after stem cells therapy for many reasons:

  • Stem cells itself will activate stem cells in the area to do their role and differentiate into mature cells that can form hair follicles.
  • ADSCs has known role increasing the blood supply by increase the number of blood vessels in the area to support sufficient oxygen and nutriments to the newly transplanted hair follicle. Also,
  • The immunosuppressive effects of ADSCs will decrease the inflammatory reaction after surgery and that by itself will improve the recovery and percentage of follicle survival.

All above will give advantage to the recipient area and increase percentage of follicle graft survival plus improve the quality of hair and shorten the time of growth.                                                             

It is important to remember that, as with all medical treatments and procedures, there is no single protocol nor single outcome for how treatments will go and what the results will be like. However, most patients are satisfied with the results of their stem cells therapy combined with other modalities of baldness treatments. Most say the researchers consider the results from using stem cells to treat hair loss have gone above and beyond what they had hoped for. Using stem cells to treat hair loss and baldness is promising to be a life-changing new field for many people in short coming future

So, the body of evidence in favour of the use of adipose derived stem cells therapy for male/female pattern hair loss is steadily growing. These therapies offer the benefit of reduced side effects compared to the current treatment modalities and appear to be effective in both males and females. With relatively no new formally approved treatments for hair loss in the last 20+ years, the future of hair restoration may lie in adipose derived stem cells therapies.

“Eyebrow Hair Transplant”

For men or women who have lost the natural full appearance of their eyebrow (permanent hair loss or thinning) and have limited response to non-surgical methods of treatment.  Last option to restore the natural and youthful eyebrow appearance is by hair transplant which is not to create perfect eyebrows shape but to significantly improve their appearance.

Who is the right candidate for an eyebrow hair transplant?

Anyone who is suffering from thinned eyebrows is considered to be good candidates for the procedure if non-surgical modalities of treatment were not satisfactory to the patients. It has to be healthy person, and in case of medical causes of eyebrow hair loss has been treated properly.

Men and women have distinguishing differences in their eyebrow. Men typically have thicker eyebrows that are horizontal. Whereas women have a more delicate and more elegant defined shape.

Proper angulation of the hair follicle is the most important feature of any eyebrow transplant. The hair in the supper part of the central edge of the eyebrow usually points upward to the hairline, while the hair on the lateral aspects points horizontally, towards the ears. The hair in the upper part of the eyebrow should pointed slightly downward and the lower portion slightly upward, so that they will coverage in the middle, forming a slight ridge and resembling the pattern of a feather.

Follicular Unit Transplantation Technique:

It provides the easiest and best surgical method for fast and simple eyebrow restoration and compared to the Strip Method as graft or flap. It is faster and easier healing, no sutures or scars, and less post-operative down time. This procedure mostly commonly for females. However, in smokers, diabetics, the elderly, and in cicatricial cases, the growth rates may be slower. Usually 80% of the transplanted hairs will grow, and of these, 10% to 15% will grow in a different direction likely due to the contracture of the skin, so need to cut or use a gel to grow in more aesthetic directions. FUE, by using single hair follicle from the central occipital area of the scalp which is the most appropriate done area, but the lateral part of the occipital region (back side of the scalp) because they contain the greatest number of single-hair follicular units with the smallest diameter.

The donor hair can be harvested by wither stip removal or Follicular Unit Extraction “FUE”. It is important to consider when FUE is used, as it is necessary to trim the donor hair, making it difficult to orient the correct angle and direction of the hairs. Generally, 200-300 follicular units are necessary for each eyebrow. In a donor strip of 1 cm width and 4-8 cm in length it is possible to obtain 400-450 pf 1-2 hair grafts.  It is also preferable to obtain the follicular units using the strip technique over FUE as it allows for the collection of longer hair (1-2 cm length).

It is simple surgical outpatient procedure done under a local anaesthesia by nerve blocks. 2- hair grafts should be implanted in the central area of the eyebrow and 1-hair graft in the external area. This pattern allows soft and natural appearance.  The angle and direction of the grafts should be individualized according to each part of the eyebrow. Important parts of it is to maintain the normal anatomical position of the eyebrow, symmetry, directional changes of the hair from inner side to outer or lateral border of the eyebrow. The precision of placement of the eyebrow hair graft is very important. Attention is paid to the creation of a lovely rise of the arch or the enhancement of the existing arch. Generally, 150-300 grafts are placed in each brow. Depending upon your individual genetic, age, cause of loss of eyebrow hairs and desired density may require more than one procedure to obtain desired look. Surgery is best spaced a minimum of 8 months apart in order to observe the full effects of the first surgery.  

Head: the most medial aspect of the head, the hairs tend to grow vertically, and the graft can be placed sparsely to accentuate a feathering appearance. Moving laterally, the hair then change from a vertical to horizontal direction of growth.

Body: along the body, the superior hairs tend to grow at a slightly inferior angle, while the inferior hairs tend to grow at a slightly superior angle, allowing a greater density and natural aspect. The tail: when the section is reached, the hairs grow horizontally in a slightly caudal direction. At the end of the tail, a second feathering zone is created by placing the finest 1-hair grafts in a progressively sparse concentration. It is very important to pay attention to the exit angle; the angle of the recipient site should be as acute as possible to allow the hairs to grow in a parallel position relative to the forehead. The growth direction of curly hair must be considered to enhance the natural effect.

Postoperative Care:

There are many recommendations for post-procedure care, including occlusion with a transparent dressing for 4 days followed by the use of petroleum jelly. 2-4 weeks post-surgery, the implanted hairs fully embed. Tinny crust that form after surgery fall off in about 10 days, bruising after surgery is common and it may take a week or more to resolve. Oedema and periorbital hematoma may occur and usually resolve in 2 days.  After that time, there is no evidence of the procedure as the transplanted follicles go into a dormant period of about 3-4 months. This is often a difficult period for patients as they eyebrow will look like it did priori to surgery. Sometimes pseudo-folliculitis can occur in the transplanted area- this usually resolves spontaneously. Occasionally, some follicles can heal with a different direction of growth to that originally intended during transplantation and require trimming. Again, patience is needed during this period.

It is necessary to cut the hairs short once to twice a week in order to obtain the ideal length and shape, as they grow quickly as your scalp hair. The transplant hair may straighten them, pluck them, was them, dye them and cut them to the desired length.

Later the eyebrow hair growth will slow down over time and the hair will begin to assume some of the characteristics of the original eyebrow hair due to influence of the recipient site.


Eyebrow restoration by hair transplant offers satisfactory aesthetic outcomes, with a 3-D effect. It is a relatively safe procedure with low morbidity. The key of its successful is to preserve the correct angle of the hairs to achieve a natural design.

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This document is designed to supply useful information but is not to be regarded as advice specific to any particular case. It does not replace the need for a thorough consultation and all prospective patients should seek the advice of a qualified physician

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