Male Pattern Baldness “MPB”

Most people shed between 75-100 scalp hairs every day from their scalp. These hairs are lost to make way for new growth hair that will soon appear.

Excessive or abnormal hair loss is known as “Alopecia“, and there are several kinds. it does not refer to a specific type of it and what all has in common, whether it’s in men or women, is that it is always a symptom of something else that’s gone wrong in your body.

Although the follicular changes that lead to alopecia are similar between men and women, clinical presentation and response to therapy are different. 

What are the common causes of MPB?

Causes can vary from genetics to the environment but, the most common type is androgenic alopeciaAGA” (Male Pattern Baldness- MPB) which account for more than 95% of hair loss in men. By the age of 35, two-third of men will experience some degree of appreciable hair loss, and by the age of 50 approximately 85% of men have significantly thinning hair.

Unbiased study among healthy men, aged 18-49 years to evaluate the incidence of moderate to extensive hair loss (Male Pattern Baldness MPB) shows that the hair fall increased with increasing age ranging from 16% for men 18-29 years of age to 53% of men 40-49. 

The strongest evidence of genetic involvement in the development of baldness in the men Male Pattern BaldnessMPB comes from studies involving the AR gene in men. A change that found in 98% of men with premature baldness and in 92% of men with late baldness, it was found in 77% of men without baldness. These elements suggest that other changes are necessary for developmental of Male Pattern Baldness, such as hormonal changes, medications, and environmental stimuli. The sufferers are actually inheriting are hair follicles with a genetic sensitivity to dihydrotestosterone (DHT). Hair follicles that are sensitive to DHT begin to miniaturize, shortening the lifespan of each hair follicle affected. Eventually, these affected follicles stop producing cosmetically acceptable hair.

What are the symptoms of MPB?

MPB is generally characterized with the onset of a receding hairline and thinning crown. Hair in these areas including the temples and mid-anterior scalp appear to be the most sensitive to DHT. This pattern eventually progresses into more apparent baldness throughout the entire top of the scalp, leaving only a rim or “horseshoe” pattern of hair remaining in the more advanced stages of MPB. For some men even, this remaining rim of hair can be affected by DHT.

Other Common Cause of Hair Loss in Men

Alopecia Areata

Alopecia areata is a hair disorder that affects about 2% of the people of the world… It is a disorder that inflicts hair loss from some areas of the body, especially the scalp. In some chronic cases, this disorder spreads to the entire scalp or epidermis.

However, alopecia areata is a hair loss condition that affects only growing hair while resting hair is not affected. Usually, a person suffering from alopecia areata makes hair follicles enter telogen resting state so that the worst effects of the disease are avoided.

With this, shedding of hair is triggered and hair follicles tend to stay in this resting stage for long periods of time. In alopecia areata, it is when the hair follicles return to an anagen growth state that the hair follicles are retargeted by the immune system and forced into a resting state.

Alopecia areata treatment reduces the action of immune cells on hair follicles

It is based on this knowledge that treatment is vested for cases of people suffering from alopecia areata where the objective of the treatment is to not only promote resting hair follicles to start growing, but to also reduce the action of immune cells on hair follicles.

Alopecia areata exists in various types; alopecia areata monolucularis is where baldness occurs in any singles spot on the head. In the case of alopecia areata multilocularis, there are multiple areas of hair loss on the scalp.

Alopecia areata is not contagious but can be contrary. Sometimes, stress too may lead to alopecia areata where the body treats hair follicles as foreign tissue.

The loss of all hair on the scalp is called Alopecia Areata Totalis while Alopecia Areata Universalis is a condition where there is loss of all body hair, including pubic hair. Diffuse alopecia areata takes place only when a person loses dark hair with psychological trauma. These people usually have only mixed grey and dark hairs.

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